Promotes: Joint Strength Liver Detoxification Mood and Brain Function. Highest Concentration of Active SS Form. Natural - Full Potency. In Foil Blister Pack. Enteric Coated Tablets. Gluten Free - Vegan. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. Contains More of the Active SS Form. Found in all living cells SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (SS) SAM-e and (RS) SAM-e. The biologically active form is the (SS) structure while the (RS) structure is biologically inactive. Jarrow FORMULAS SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (SS) SAM-e the highest active level available. SAM-e has been clinically shown to have the following benefits:. Joint Strength - SAM-e supports the production of healthy connective tissue through transulfuration. In this process critical components of connective tissue including glucosamine and the chondroitin sulfates are sulfated by SAM-e metabolites. Brain Metabolism - SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA dopamine and related hormones epinephrine and phosphatidylcholine (a component of lecithin). Longevity - Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity. Liver - SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase) which are substances important for liver function.
"I have taken in the past GNC SAM-e, though this was when they used the better absorbed formula. I had to break in half 200mg tablets because the effect was so strong. I took #2 200 mg of the Jarrow SAM-e and felt nothing and I used it for 10 days. Consumer Reports reviewed many companies who make SAM-e and found several who had little or no active ingredient. I will never buy this SAM-e again!"
"Good product at a great price. This product helped with my mood. I had to discontinue taking it though due to side effects of light headedness and dizziness that was persistant after taking it a while. I happen to be very sensitive to products,this was my experience it may not effect others this way."