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Top Rated Product
NSI SAM-e -- 400 mg - 30 Tablets

NSI SAM-e -- 400 mg - 30 Tablets

A European, pharmaceutical quality SAM-e found to promote healthy mood, liver and joint function. A powerful, natural nutrient, S-adenosyl methionine (SAM-e) promotes healthy mood, liver and joint function. NSI® SAM-e is pharmaceutical quality, full potency, and stabilized. SAM-e supplements contain amounts of both the active SS form and the inactive RS form. NSI SAM-e undergoes a natural process of microbiological fermentation, and is then specially processed without solvents. This process ensures an active SS level of 68-80%, the highest concentration available. SAM-e supplementation may benefit aging people, as they are prone to experience joint discomfort. SAM-e is believed to raise the levels of specific neurotransmitters, especially that of dopamine, which is important for mood regulation. SAM-e boosts natural antioxidant levels, and may provide benefits for liver health. In the liver, SAM-e supports the improved flow of bile and replenishes important antioxidants. The typical SAM-e dosage is 400-800 mg daily for promoting a healthy mood, liver and joints. It should be consumed as a tablet that is enteric-coated and is in the stabilized and standardized form. As SAM-e is 50% elemental, a product must provide 800 mg gross to equal 400 mg elemental, thereby making it beneficial. NSI® SAM-e 400 mg (from 800 mg gross) contains 30 enteric-coated tablets.  . Did You Know? All NSI supplements are packaged in HDPE (High Density Polyethylene) bottles. These bottles keep moisture vapor out, protecting the freshness and integrity of their contents, and are 400% more effective compared other brands currently using PET (Polyethylene Terephthalate) bottles. HDPE bottles do not break as glass can and are also recyclable so we urge you to please recycle them.  

Average Customer Rating: 4.52 out of 5 4.5 out of 5
91 of 100 (91%) customers would recommend this product to a friend.

Customer Reviews for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
Great Product., May 11, 2009
By vitgal
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"I think it is even better then others just like it on the market. Plus the price is Great."

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Review 2 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
March 26, 2009
By EREED
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"This product really works on my inflamed joints"

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Review 3 for NSI SAM-e -- 400 mg - 30 Tablets

Top 250 Contributor Top 250 Contributor
Overall Rating: 5 out of 5 5 out of 5
Great Value, March 24, 2009
By jwelston from Virginia
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"Sam e has helped my joints a great deal. NSI again provides a quality product for a great price. Sam e additional benefits seem to work well also. Next to my fish oil, this may be the most helpful."

Age: 35-44
Gender: Male
Daily supplement usage: 6+ supplements daily
Referral source: Self-referred
Reason for usage: Promote overall health
Duration of use: Over 180 days
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Review 4 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
NSI SAMe 400 mg., February 9, 2009
By tanguera
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"I am pleased with the effectiveness of this version of SAMe. Not all varieties of this product are effective, but this one is. It is a good value for the price, also."

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Review 5 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
Its for my Dog, December 29, 2008
By Thunder
Value: 5 out of 5 5 out of 5
Quality: 4 out of 5 4 out of 5
Effectiveness: 4 out of 5 4 out of 5
Satisfaction: 4 out of 5 4 out of 5

"I give this to my dog who had elevated liver levels and it has helped him greatly. My vet reccomended it."

2 of 2 people found this review helpful.
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Review 6 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
Love this product, December 23, 2008
By cmkal from Omaha, NE
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"I have way less joint pain than I used to have, less depression, and I cannot believe how well I am sleeping. I used to sleep 3-4 hours a night, now I sleep an easy 8, thank god!"

Age: 45-54
Gender: Female
Daily supplement usage: 3-5 supplements daily
Reason for usage: Specific health concern
Duration of use: 61-180 days
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Review 7 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
Love this stuff, December 22, 2008
By Irfie from Washington State
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"I have fibromyalgia and mood swings because of it and SamE helps so much with it. I can't do without it. I have tried and notice the difference right away. This is the best place to buy it. I really like NSI. Their products have all worked well for me."

Age: 55-64
Gender: Female
Daily supplement usage: 6+ supplements daily
Referral source: Physician
Reason for usage: Specific health concern
Duration of use: Over 180 days
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Review 8 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 2 out of 5 2 out of 5
Non-effective product, November 30, 2008
By Samir
Value: 1 out of 5 1 out of 5
Quality: 2 out of 5 2 out of 5
Effectiveness: 1 out of 5 1 out of 5
Satisfaction: 1 out of 5 1 out of 5

"Though DMAE is supposed to be a precursor to citicoline, I found this product (at least this product) to bring about the opposite effects, as experirnced by taking citicoline. Experirnced extreme drowsiness, became letharigic.

Would not recommend it to anyone !!!"


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Review 9 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 1 out of 5 1 out of 5
no so great, November 18, 2008
By liarose from massapequa,ny
Value: 3 out of 5 3 out of 5
Quality: 2 out of 5 2 out of 5
Effectiveness: 1 out of 5 1 out of 5
Satisfaction: 1 out of 5 1 out of 5

"this product did nothing for me. i was looking for something to help my mood.didnt work for me"

Age: 35-44
Gender: Female
Daily supplement usage: 1-2 supplements daily
Referral source: Self-referred
Reason for usage: Promote overall health
Duration of use: Less than 30 days
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Review 10 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
Sam-e, November 13, 2008
By jon101 from Forest, VA
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"Since taking these my dogs liver levels are returning to within the reference range"

Age: 35-44
Gender: Male
Daily supplement usage: 1-2 supplements daily
Referral source: Other
Reason for usage: Specific health concern
Duration of use: 30-60 days
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Review 11 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
the best, October 14, 2008
By extraodinaire from new
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"This product keeps me calm and I have less cramping in my feet. NSI BRAND products are just the best. I have been using herbal formulas for over 25 years, and have been using NSI for the last 4 years. NSI quality & quantity for the cost just cant be beat. These doctors are knowledgeable, honest, and have a high level of integrity. I'm a customer for life"

Age: 45-54
Gender: Female
Daily supplement usage: 6+ supplements daily
Referral source: Self-referred
Duration of use: Less than 30 days
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Review 12 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 1 out of 5 1 out of 5
SAM-e, September 13, 2008
By chief5 from Glenwood Springs, CO
Value: 4 out of 5 4 out of 5
Quality: 4 out of 5 4 out of 5
Effectiveness: 1 out of 5 1 out of 5
Satisfaction: 1 out of 5 1 out of 5

"I used this product for about a week and found it upset my stomach terribly. I discontinued it and I was back to normal. I switched to NSI 5-HTP and it is working just fine without the side effects."

Age: 45-54
Gender: Male
Daily supplement usage: 6+ supplements daily
Referral source: Physician
Reason for usage: Specific health concern
Duration of use: Less than 30 days
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Review 13 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
Great Stuff!, August 28, 2008
By bluzman58 from Gwinn, Michigan
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"This product was recommended to me by my physical therapist as a nautral alternative to NSAIDs and it is great! I started noticing less pain and a little more joint mobility within a very short time (2-3 days) after I started taking it. Highly recommended!"

Age: 45-54
Gender: Male
Daily supplement usage: 3-5 supplements daily
Referral source: Other
Reason for usage: Promote overall health
Duration of use: 30-60 days
1 of 1 people found this review helpful.
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Review 14 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 3 out of 5 3 out of 5
Good But Can Leak When Out of Package, August 27, 2008
By jxjx
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 3 out of 5 3 out of 5

"The product is satisfactory, but cannot be placed in daily use containers because it soon starts to leak. So, it must be carried in its own large, bulky container or foil pack until taken."

Duration of use: Over 180 days
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Review 15 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
works like it should, August 3, 2008
By madlove

"if you have tried glusomine and chondrotine you should try this. Much better results and does help the mood too. Knees and joints have been great since i started this product one month ago."

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Review 16 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
wonderful product, July 22, 2008
By crayon from Tulsa, OK
Value: 4 out of 5 4 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"this product has kept me on an even level
I no longer sweat the small stuff
I am in good mood every day
I LOVE IT!
WONT GO 1 DAY WITHOUT IT!!!!"


Age: 45-54
Gender: Female
Daily supplement usage: 1-2 supplements daily
Referral source: Self-referred
Reason for usage: Enhanced performance
Duration of use: 30-60 days
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Review 17 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 4 out of 5 4 out of 5
Just starting it...., July 19, 2008
By Fodor from Pittsburgh, PA
Value: 4 out of 5 4 out of 5
Quality: 4 out of 5 4 out of 5
Effectiveness: 4 out of 5 4 out of 5
Satisfaction: 4 out of 5 4 out of 5

"I haven't been taking the stuff very long so I can't say that it warrants 5-stars. But I do seem to be tolerating it pretty well. You do have to be careful to learn to take it on an empty stomach, unlike with most supplements."

Age: 45-54
Gender: Male
Daily supplement usage: 3-5 supplements daily
Referral source: Self-referred
Reason for usage: Promote overall health
Duration of use: Less than 30 days
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Review 18 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 2 out of 5 2 out of 5
Maybe, maybe not, June 24, 2008
By jpsprings from Palm Springs, CA
Value: 2 out of 5 2 out of 5
Quality: 2 out of 5 2 out of 5
Effectiveness: 2 out of 5 2 out of 5
Satisfaction: 2 out of 5 2 out of 5

"I've been using this for 5 weeks; I can't really detect much of an effect. It could just as well be a placebo.

I previously tried the Jarrow brand of SAM-e; I think that brand works better for me."


Age: 45-54
Gender: Male
Daily supplement usage: 1-2 supplements daily
Referral source: Self-referred
Duration of use: 30-60 days
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Review 19 for NSI SAM-e -- 400 mg - 30 Tablets

Overall Rating: 5 out of 5 5 out of 5
sam-e, June 18, 2008
By jag33 from WA
Value: 5 out of 5 5 out of 5
Quality: 5 out of 5 5 out of 5
Effectiveness: 5 out of 5 5 out of 5
Satisfaction: 5 out of 5 5 out of 5

"An RN recommended that I take sam-e to help level out my emotions during a recent time when one of my parents passed away. I've been very pleased with this sam-e. The cost is good, the dosage is good and it seems to be helping. It is nice to be able to take 400mg in one pill instead of some of the lower dose pills."

Age: 35-44
Gender: Female
Daily supplement usage: 1-2 supplements daily
Referral source: Friend
Reason for usage: Specific health concern
Duration of use: 61-180 days
1 of 1 people found this review helpful.
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Review 20 for NSI SAM-e -- 400 mg - 30 Tablets

Top 100 Contributor Top 100 Contributor
Overall Rating: 4 out of 5 4 out of 5
NSI SAMe, June 1, 2008
By AtlantaJJ from Atlanta, GA
Value: 5 out of 5 5 out of 5
Quality: 3 out of 5 3 out of 5
Effectiveness: 3 out of 5 3 out of 5
Satisfaction: 3 out of 5 3 out of 5

"It's not bad but I noticed a huge difference when I switched to the Jarrow brand...which they don't have in stock...hmmmm.... It's worth a try if you haven't used SAMe and I beleive you get some benefit, but the best I have tried is Jarrow.
Great price ...."


Age: 45-54
Gender: Female
Daily supplement usage: 6+ supplements daily
Referral source: Self-referred
Reason for usage: Promote overall health
Duration of use: 30-60 days
2 of 2 people found this review helpful.
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