Drug-Free Nighttime Sleep Aid. Melatonin with Vitamin B6 Promotes Normal Sleep Patterns. Natrol® Melatonin is a 100% vegetarian drug-free sleep aid for relief of occasional sleeplessness. Melatonin helps establish normal sleep patterns to promote a more restful relaxing sleep and better overall health. The body naturally produces melatonin and Vitamin B6 is essential for melatonin production.