Promotes Healthy Homocysteine Levels. 500 MG. Trimethylglycine (TMG) is also called glycine betaine but the name trimethylglycine signifies the it has three methyl groups attached to each molecule of gycine. TMG was discovered to be beneficial to heart health back in the 1950s. TMG operates along a pathway similar to that of vitamin B12: It is a "methyl donor" providing extra methyl groups to hasten the conversion of homocysteine back to methionine. When a TMG methyl group is donated to a molecule of homocysteine it converts to the non-toxic amino acid methionine. Research showing TMG's ability t o promote healthy levels of homocysteine alone or in conjunction with other nutrients confirms its status as an important nutrient for cardiovascular health. For example in a recent cross-sectional survey study participants who consumed >360 mg/d of TMG had on average 10% lower concentrations of homcysteine and 19% lower concentrations of C-reactive protein than those who consumed < 260 mg/d.
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